Application of toxicogenomics to cross-species extrapolation : report of a workshop /

Corporate Author: National Research Council (U.S.). Committee on Applications of Toxicogenomics to Cross-Species Extrapolation.
Format: Book
Language:English
Published: Washington, D.C. : National Academies Press, ©2006.
Subjects:
Online Access:http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=159586
Table of Contents:
  • Emerging molecular and computational approaches for cross-species extrapolation
  • Potential implications of genomics for risk assessment
  • Technological challenges of cross-species extrapolation using proteomics
  • Modeling gene-expression data to predict human hepatotoxicity after inconsistent animal responses
  • Using metabolomics to explore species differences in metabolism and distribution
  • A systems-biology approach to cross-species extrapolation
  • Combining transcriptional and toxicologic approaches to understanding the basis of species differences in conazole carcinogenesis
  • Species differences in response to perfluorooctanoic acid.